Prescribing errors (PEs) in the in-hospital setting, resulting from inappropriately prescribed medication, can cause adverse drug events (ADEs) resulting in patient harm, prolonged hospital stay and hospital readmission. Over the past decades, this challenge remains a worldwide topic of awareness resulting in the development of several intervention strategies. Despite, numbers are not declining. Development of such strategies requires insight and understanding of factors influencing in-hospital prescribing process. In this thesis we will explore a multifaceted in-hospital intervention by a multidisciplinary team, consisting of stakeholders in the in-hospital prescribing process - medical doctors and pharmacists. We hypothesize that this thesis will provide insight at which points in the chain of prescribing PEs occur, what their root causes are, what risk factors are for PEs and what the effect is of such a multidisciplinary in-hospital team.